FLNC (gene)

FLNC
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFLNC, ABP-280, ABP280A, ABPA, ABPL, FLN2, MFM5, MPD4, filamin C, RCM5, CMH26
External IDsOMIM: 102565; MGI: 95557; HomoloGene: 37481; GeneCards: FLNC; OMA:FLNC - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001458
NM_001127487

NM_001081185
NM_001311074
NM_026839

RefSeq (protein)

NP_001120959
NP_001449

NP_001074654
NP_001298003

Location (UCSC)Chr 7: 128.83 – 128.86 MbChr 6: 29.43 – 29.46 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Filamin-C (FLN-C) also known as actin-binding-like protein (ABPL) or filamin-2 (FLN2) is a protein that in humans is encoded by the FLNC gene.[5][6][7] Filamin-C is mainly expressed in cardiac and skeletal muscles, and functions at Z-discs and in subsarcolemmal regions.

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000128591Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000068699Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Maestrini E, Patrosso C, Mancini M, Rivella S, Rocchi M, Repetto M, Villa A, Frattini A, Zoppè M, Vezzoni P (June 1993). "Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7". Human Molecular Genetics. 2 (6): 761–6. doi:10.1093/hmg/2.6.761. PMID 7689010.
  6. ^ Gariboldi M, Maestrini E, Canzian F, Manenti G, De Gregorio L, Rivella S, Chatterjee A, Herman GE, Archidiacono N, Antonacci R (May 1994). "Comparative mapping of the actin-binding protein 280 genes in human and mouse". Genomics. 21 (2): 428–30. doi:10.1006/geno.1994.1288. PMID 8088838.
  7. ^ "Entrez Gene: FLNC filamin C, gamma (actin binding protein 280)".