FOXN1

FOXN1
Identifiers
Aliases	FOXN1, FKHL20, RONU, WHN, forkhead box N1, TIDAND, TLIND
External IDs	OMIM: 600838; MGI: 102949; HomoloGene: 2664; GeneCards: FOXN1; OMA:FOXN1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	28,538,900 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	78,277,384 bp
RNA expression pattern
	Top expressed in
	gingival epithelium; ; skin of thigh; ; skin of abdomen; ; human penis; ; skin of hip; ; vulva; ; nipple; ; oral cavity; ; mucosa of pharynx; ; vagina;
	Top expressed in
	hair; ; outer root sheath of hair follicle; ; cortex of hair; ; lip; ; filiform papilla; ; thymus; ; skin of back; ; skin of abdomen; ; morula; ; embryo;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	sequence-specific DNA binding; DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus;
Biological process	hair follicle development; defense response; nail development; regulation of transcription, DNA-templated; blood vessel morphogenesis; thymus epithelium morphogenesis; thymus development; regulation of transcription by RNA polymerase II; lymphocyte homeostasis; positive regulation of hair follicle development; epithelial cell proliferation; transcription by RNA polymerase II; transcription, DNA-templated; regulation of positive thymic T cell selection; keratinocyte differentiation; lymphoid lineage cell migration into thymus; T cell homeostasis; multicellular organism development; regulation of T cell differentiation in thymus; epidermis development; animal organ morphogenesis; regulation of gene expression; cell population proliferation; T cell lineage commitment; positive regulation of epithelial cell differentiation; cell differentiation; positive regulation of transcription by RNA polymerase II; hemopoiesis;
	Sources:Amigo / QuickGO
Orthologs
	8456
	15218
	ENSG00000109101
	ENSMUSG00000002057
	O15353
	Q61575
	NM_003593; NM_001369369
	NM_001277290; NM_008238
	NP_003584; NP_001356298
	NP_001264219; NP_032264
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box protein N1 is a protein that in humans is encoded by the FOXN1 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000109101 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000002057 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Schorpp M, Hofmann M, Dear TN, Boehm T (Dec 1997). "Characterization of mouse and human nude genes". Immunogenetics. 46 (6): 509–15. doi:10.1007/s002510050312. PMID 9321431. S2CID 32175138.
^ "Entrez Gene: FOXN1 forkhead box N1".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000109101 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000002057 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9321431-5] Schorpp M, Hofmann M, Dear TN, Boehm T (Dec 1997). "Characterization of mouse and human nude genes". Immunogenetics. 46 (6): 509–15. doi:10.1007/s002510050312. PMID 9321431. S2CID 32175138.

[entrez-6] "Entrez Gene: FOXN1 forkhead box N1".

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