Fat necrosis

Fat necrosis
Other namesalso known as Balser's necrosis
Micrograph of breast tissue showing fat necrosis. H&E stain
SpecialtyPathology

Fat necrosis is necrosis affecting fat tissue (adipose tissue).[1] The term is well-established in medical terminology despite not denoting a specific pattern of necrosis.[2] Fat necrosis may result from various injuries to adipose tissue, including: physical trauma, enzymatic digestion of adipocytes by lipases,[3] radiation therapy,[4] hypoxia, or inflammation of subcutaneous fat (panniculitis).

The gross appearance of fat necrosis is as an irregular, chalky white area within otherwise normal adipose tissue.[1]

  1. ^ a b Strayer, David S.; Rubin, Emanuel; Saffitz, Jeffrey E.; Schiller, Alan L., eds. (2015). Rubin's Pathology: Clinicopathologic Foundations of Medicine (7th ed.). Philadelphia: Wolters Kluwer Health. pp. 34–35. ISBN 978-1-4511-8390-0.
  2. ^ Kumar, Vinay; Abbas, Abul K.; Aster, Jon C., eds. (2015). Robbins and Cotran pathologic basis of disease (Ninth ed.). Philadelphia, PA: Elsevier/Saunders. pp. 43–44. ISBN 978-1-4557-2613-4.
  3. ^ Cross, Simon S. (2013). Underwood's Pathology (6th ed.). Churchill Livingstone. p. 85. ISBN 978-0-7020-4672-8.
  4. ^ "fat necrosis". www.cancer.gov. 2011-02-02. Retrieved 2024-06-16.