Fenthion

Fenthion[1]
Names
Preferred IUPAC name
O,O-Dimethyl O-[3-methyl-4-(methylsulfanyl)phenyl] phosphorothioate
Other names
• Dimethoxy-[3-methyl-4-(methylthio)phenoxy]-thioxophosphorane
O,O-Dimethyl O-[3-methyl-4-(methylthio)phenyl] phosphorothioate
O,O-Dimethyl O-4-methylthio-m-tolyl phosphorothioate
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.211 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C10H15O3PS2/c1-8-7-9(5-6-10(8)16-4)13-14(15,11-2)12-3/h5-7H,1-4H3 checkY
    Key: PNVJTZOFSHSLTO-UHFFFAOYSA-N checkY
  • InChI=1/C10H15O3PS2/c1-8-7-9(5-6-10(8)16-4)13-14(15,11-2)12-3/h5-7H,1-4H3
    Key: PNVJTZOFSHSLTO-UHFFFAOYAH
  • S=P(OC)(OC)Oc1ccc(SC)c(c1)C
Properties
C10H15O3PS2
Molar mass 278.33 g/mol
Appearance colorless, almost odorless liquid; 95-98% pure fenthion is a brown oily liquid with a weak garlic odor
Density 1.250 g/cm3 (at 20 °C / 4 °C)
Melting point 7 °C (45 °F; 280 K)
Boiling point 87 °C (189 °F; 360 K) at 0.01 mmHg
54-56 ppm (at 20 °C)
Solubility in glyceride oils, methanol, ethanol, ether, acetone, and most organic solvents, especially chlorinated hydrocarbons soluble
Vapor pressure 4 • 10−5 mmHg (at 20 °C)
Pharmacology
QP53BB02 (WHO)
Hazards
NIOSH (US health exposure limits):
PEL (Permissible)
none[2]
REL (Recommended)
None established[2]
IDLH (Immediate danger)
N.D.[2]
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Fenthion is an organothiophosphate insecticide, avicide, and acaricide. Like most other organophosphates, its mode of action is via cholinesterase inhibition. Due to its relatively low toxicity towards humans and mammals, fenthion is listed as moderately toxic compound in U.S. Environmental Protection Agency and World Health Organization toxicity class.[1][3]

  1. ^ a b HSDB. (2003). Hazardous Substance Data Bank: Fenthion. National Library of Medicine: National Toxicology Program. Available at http://toxnet.nlm.nih.gov/cgi-bin/sis/htmlgen?HSDB Accessed April 29, 2009.
  2. ^ a b c NIOSH Pocket Guide to Chemical Hazards. "#0285". National Institute for Occupational Safety and Health (NIOSH).
  3. ^ EXTOXNET. (2003). Pesticide information Profile for Fenthion. Cooperative Extension Offices of Cornell University, Michigan State University, Oregon State University, and University of California at Davis. Available at http://pmep.cce.cornell.edu/profiles/extoxnet/dienochlor-glyphosate/fenthion-ext.html Accessed April 25, 2009.