Fibromatosis

Fibromatosis
The cut surface of desmoid-type fibromatosis is firm, white, and whorled. The white tumor infiltrates the adjacent skeletal muscle (red tissue – lower left) and fat (yellow tissue – upper left). This tendency for invasion of adjacent normal tissues and structures is the reason that desmoid-type fibromatosis has a relatively high rate of local recurrence, even after surgical removal.
SpecialtyOncology

The term fibromatosis refers to a group of soft tissue tumors[1] which have certain characteristics in common, including absence of cytologic and clinical malignant features, a histology consistent with proliferation of well-differentiated fibroblasts, an infiltrative growth pattern, and aggressive clinical behavior with frequent local recurrence. It is classed by the World Health Organization as an intermediate soft tissue tumor related to the sarcoma family. Arthur Purdy Stout coined the term fibromatosis (in the name congenital generalized fibromatosis, describing myofibromatosis), in 1954.[2]

  1. ^ "fibromatosis" at Dorland's Medical Dictionary
  2. ^ Beck, Jill C.; Devaney, Kenneth O.; Weatherly, Robert A.; Koopmann, Charles F.; Lesperance, Marci M. (1999-01-01). "Pediatric Myofibromatosis of the Head and Neck". Archives of Otolaryngology–Head & Neck Surgery. 125 (1): 39. doi:10.1001/archotol.125.1.39. ISSN 0886-4470. PMID 9932585.