| First Lady of Guyana | |
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| Residence | State House, Georgetown, Guyana |
| Inaugural holder | Doreen Chung |
| Formation | March 17, 1970 |
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First Lady of Guyana is the title held by the wife of the president of Guyana. The current first lady of Guyana is Arya Ali, wife of President Irfaan Ali, who has served in the position since August 2020.