| Florida Panther National Wildlife Refuge | |
|---|---|
IUCN category IV (habitat/species management area) | |
 Florida panther | |
  | |
| Location | Collier County, Florida, U.S. |
| Nearest city | Naples |
| Coordinates | 26°10′20″N 081°22′38″W / 26.17222°N 81.37722°W |
| Area | 26,400 acres (107 km2) |
| Established | 1989 |
| Governing body | US Fish & Wildlife Service |
| Website | Florida Panther National Wildlife Refuge |
The Florida Panther National Wildlife Refuge is part of the United States National Wildlife Refuge System, located in southwestern Florida, twenty miles east of Naples, in the upper segment of the Fakahatchee Strand of the Big Cypress Swamp. It is north of I-75 and west of SR 29.