Florida State Road 45

State Road 45 marker
State Road 45
Route information
Maintained by FDOT
Length300.547 mi[1] (483.684 km)
Major junctions
South end US 41 in Naples
North end US 41 / US 441 in High Springs
Location
CountryUnited States
StateFlorida
CountiesCollier, Lee, Charlotte, Sarasota, Manatee, Hillsborough, Pasco, Hernando, Citrus, Marion, Levy, Alachua
Highway system
SR 44SR 45, SR 45A SR 46

A major north–south highway extending almost the entire length of the Florida peninsula, State Road 45 (SR 45) is the unsigned Florida Department of Transportation designation of most of the current U.S. Route 41 in Florida. The southern terminus of SR 45 is an intersection with SR 90 in downtown Naples; the northern terminus is an intersection with US 441 (SR 25) in High Springs. South of Causeway Boulevard (SR 676) near Tampa, SR 45 is also known as the Tamiami Trail.

South and east of Naples, US 41 turns eastward as SR 90 as the Tamiami Trail crosses the Everglades on its way to Miami; north of High Springs, US 41 overlaps US 441 (SR 25) until their split in Lake City (from there US 41 continues to the Georgia border with the hidden SR 25 designation).

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