Names | |
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Preferred IUPAC name
3-Chloro-N-[3-chloro-2,6-dinitro-4-(trifluoromethyl)phenyl]-5-(trifluoromethyl)pyridin-2-amine | |
Identifiers | |
3D model (JSmol)
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ChEBI | |
ChemSpider | |
ECHA InfoCard | 100.114.073 |
PubChem CID
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UNII | |
CompTox Dashboard (EPA)
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Properties | |
C13H4Cl2F6N4O4 | |
Molar mass | 465.09 g·mol−1 |
Density | 1.8±0.1 g/cm3 |
Melting point | 116 °C (241 °F; 389 K) |
Boiling point | 376.1±42.0°C (Predicted) |
1.76 mg/L | |
Vapor pressure | 5.51×10−8 mmHg (Predicted) |
Hazards | |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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5000mg/kg (rat, oral) 4190mg/kg (mallard, oral) ≥200μg (bee, contact) ≥1000mg/kg (worm, 28 day) |
LC50 (median concentration)
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61ppb (rainbow trout, 96h) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Fluazinam is a broad-spectrum fungicide used in agriculture. It is classed as a diarylamine and more specifically an arylaminopyridine. Its chemical name is 3-chloro-N-(3-chloro-2,6-dinitro-4-trifluoromethylphenyl)-5-trifluoromethyl-2-pyridinamine.[1] The mode of action involves the compound being an extremely potent uncoupler of oxidative phosphorylation in mitochondria[2] and also having high reactivity with thiols.[1] It is unique amongst uncouplers in displaying broad-spectrum activity against fungi and also very low toxicity to mammals due to it being rapidly metabolised to a compound without uncoupling activity.[1][3] It was first described in 1992 and was developed by researchers at the Japanese company Ishihara Sangyo Kaisha.[4]