Fluciclovine (18F)

Fluciclovine (18F)
Clinical data
Trade namesAxumin
AHFS/Drugs.comMicromedex Detailed Consumer Information
License data
ATC code
Legal status
Legal status
Identifiers
  • trans-1-Amino-3-(18F)fluorocyclobutanecarboxylic acid
CAS Number
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC5H818FNO2
Molar mass132.12 g·mol−1
3D model (JSmol)
  • N[C@]1(C[C@H]([18F])C1)C(O)=O
  • InChI=1S/C5H8FNO2/c6-3-1-5(7,2-3)4(8)9/h3H,1-2,7H2,(H,8,9)/t3-,5-/i6-1
  • Key:NTEDWGYJNHZKQW-DGMDOPGDSA-N

Fluciclovine (18F), also known as anti-1-amino-3-18F-fluorocyclobutane-1-carboxylic acid (anti-3[18F] FACBC),[3][4] and sold under the brand name Axumin, is a diagnostic agent used for positron emission tomography (PET) imaging in men with suspected prostate cancer recurrence based on elevated prostate specific antigen (PSA) levels.[5][6]

  1. ^ "Axumin- fluciclovine f-18 injection, solution". DailyMed. 8 December 2023. Retrieved 15 May 2024.
  2. ^ "Axumin EPAR". European Medicines Agency (EMA). 22 May 2017. Retrieved 15 May 2024.
  3. ^ Cite error: The named reference Schiavina2013 was invoked but never defined (see the help page).
  4. ^ Cite error: The named reference Forrest2014 was invoked but never defined (see the help page).
  5. ^ Cite error: The named reference FDA20160527 was invoked but never defined (see the help page).
  6. ^ Cite error: The named reference Drugs was invoked but never defined (see the help page).