Fluoroacetamide

Fluoroacetamide
Skeletal formula of fluoroacetamide
Ball-and-stick model of fluoroacetamide
Names
IUPAC name
2-Fluoroacetamide
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.010.331 Edit this at Wikidata
KEGG
UNII
  • InChI=1S/C2H4FNO/c3-1-2(4)5/h1H2,(H2,4,5) checkY
    Key: FVTWJXMFYOXOKK-UHFFFAOYSA-N checkY
  • InChI=1/C2H4FNO/c3-1-2(4)5/h1H2,(H2,4,5)
    Key: FVTWJXMFYOXOKK-UHFFFAOYAA
  • C(C(=O)N)F
  • FCC(=O)N
Properties
FCH2CONH2
Molar mass 77.058 g·mol−1
Appearance Colorless crystals
Melting point 107 to 109 °C (225 to 228 °F; 380 to 382 K)
Soluble
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Very toxic
GHS labelling:
GHS06: Toxic
Danger
H300+H310
P262, P264, P270, P280, P301+P310+P330, P302, P350, P362, P405, P501
NFPA 704 (fire diamond)
NFPA 704 four-colored diamondHealth 4: Very short exposure could cause death or major residual injury. E.g. VX gasFlammability 1: Must be pre-heated before ignition can occur. Flash point over 93 °C (200 °F). E.g. canola oilInstability (yellow): no hazard codeSpecial hazards (white): no code
4
1
Lethal dose or concentration (LD, LC):
80 mg/kg (dermal, rat)
550 mg/m3(mouse, inhalation, dust/mist)
Safety data sheet (SDS) [1]
Related compounds
Related compounds
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Fluoroacetamide is an organic compound with the chemical formula FCH2CONH2. It is a compound based on acetamide with one fluorine atom replacing hydrogen on the methyl group. It is very toxic.[1] It is a metabolic poison which disrupts the citric acid cycle and was used as a rodenticide.[2] May cause reproductive disorders. If swallowed or in contact with skin, it can cause serious damage and death. Can cause serious eye damage.[1]

  1. ^ a b c https://www.sigmaaldrich.com/US/en/sds/aldrich/128341?userType=anonymous [bare URL]
  2. ^ MATSUMURA F, O'BRIEN RD. A COMPARATIVE STUDY OF THE MODES OF ACTION OF FLUOROACETAMIDE AND FLUOROACETATE IN THE MOUSE AND AMERICAN COCKROACH. Biochem Pharmacol. 1963 Oct;12:1201-5.doi:10.1016/0006-2952(63)90095-9 PMID 14074120