| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Human |
| Target | CD3 epsilon |
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Foralumab (TZLS-401), being researched by Tiziana Life Sciences[1]) is a fully human monoclonal antibody that binds to CD3 epsilon of the T cell receptor-CD3 complex.[2] It is currently being studied in a randomized, double-blind placebo-controlled, multicenter dose-ranging study in a nasal formulation in patients with non-active secondary progressive multiple sclerosis (SPMS).[1]
- ^ a b Tiziana Life Sciences LTD (2024-03-15). A Phase 2a Randomized, Double-Blind, Placebo-Controlled, Multicenter Dose-Ranging Study of Nasal Foralumab in Non-Active Secondary Progressive Multiple Sclerosis Patients (Report). clinicaltrials.gov.
- ^ World Health Organization (2010). "International Nonproprietary Names for Pharmaceutical Substances (INN). Proposed INN: List 103" (PDF). WHO Drug Information.