Fork head domain

Fork head domain
Structure of the winged helix protein Genesis.[1]
Identifiers
SymbolFork_head
PfamPF00250
InterProIPR001766
SMARTSM00339
PROSITEPDOC00564
SCOP22hfh / SCOPe / SUPFAM
CDDcd00059
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
PDB1d5v​, 1e17​, 1jxs​, 1kq8​, 2a3s​, 2c6y​, 2d2w​, 2hdc​, 2hfh

The fork head domain is a type of protein domain that is often found in transcription factors and whose purpose is to bind DNA.[2]

  1. ^ Marsden I, Jin C, Liao X (May 1998). "Structural changes in the region directly adjacent to the DNA-binding helix highlight a possible mechanism to explain the observed changes in the sequence-specific binding of winged helix proteins". J. Mol. Biol. 278 (2): 293–9. doi:10.1006/jmbi.1998.1703. PMID 9571051.
  2. ^ Kaufmann E, Knöchel W (June 1996). "Five years on the wings of fork head". Mech. Dev. 57 (1): 3–20. doi:10.1016/0925-4773(96)00539-4. PMID 8817449. S2CID 18056224.