Bronze denaro of Francesco II, with the Gattilusi arms and the tetragrammic cross of the Byzantine Empire
Relief at the Castle of Mytilene, showing the eagle of the Doria family (far left), the family cypher of the Palaiologoi (center left), and the Gattilusi coat of arms (center right)
Francesco II Gattilusio (born Giacomo Gattilusio or Jacopo c. 1365 – 26 October 1403/1404) was the second Gattilusio lord of Lesbos, from 1384 to his death. He was the third son of Francesco I Gattilusio and Maria Palaiologina, the sister of the Byzantine emperor John V Palaiologos.
