Fred W. McLafferty | |
|---|---|
| Born | May 11, 1923 Evanston, Illinois, U.S. |
| Died | December 26, 2021 (aged 98) Ithaca, New York, U.S. |
| Alma mater | University of Nebraska (BS, 1943 MS, 1947) Cornell University (PhD, 1950) University of Iowa (PostDoc) |
| Known for | Gas chromatography–mass spectrometry McLafferty rearrangement |
| Awards | ACS Award in Chemical Instrumentation (1971) Fisher Award (1981) Member of the National Academy of Sciences (1982) William H. Nichols Medal (1984) Oesper Award (1985) Sir J.J. Thomson Gold Medal (1985) Field and Franklin Award (1989) ASMS Distinguished Contribution in Mass Spectrometry Award (2003) Lavoisier Medal (2004)[1] |
| Scientific career | |
| Fields | Chemist |
| Institutions | Purdue University Cornell University |
| Doctoral students | |
| External videos | |
|---|---|
 “A Conversation with Fred W. McLafferty”, Cornell University, 2006, 90 minute video |
Fred Warren McLafferty (May 11, 1923 − December 26, 2021) was an American chemist known for his work in mass spectrometry. He is best known for the McLafferty rearrangement reaction that was observed with mass spectrometry.[4] With Roland Gohlke, he pioneered the technique of gas chromatography–mass spectrometry.[5][6] He is also known for electron-capture dissociation, a method of fragmenting gas-phase ions.[7]
- ^ "Seven Cornellians receive prestigious national and international honors". Cornell Chronicle. December 3, 2004. Retrieved 2014-08-28.
- ^ "Advisory Board". aamsdg.emory.edu. Retrieved 2021-12-29.
- ^ "Neil Kelleher – Kelleher Research Group". Archived from the original on 2022-11-16. Retrieved 2021-12-29.
- ^ F. W. McLafferty (1959). "Mass Spectrometric Analysis. Molecular Rearrangements". Analytical Chemistry. 31 (1): 82–87. doi:10.1021/ac60145a015.
- ^ Jones, Mark. "Gas Chromatography-Mass Spectrometry". American Chemical Society. Retrieved 19 Nov 2019.
- ^ Gohlke, Roland S.; McLafferty, Fred W. (1993). "Early gas chromatography/mass spectrometry". Journal of the American Society for Mass Spectrometry. 4 (5): 367–371. Bibcode:1993JASMS...4..367G. doi:10.1016/1044-0305(93)85001-E. PMID 24234933.
- ^ Zubarev, R. A.; Kelleher, N. L.; McLafferty, F. W. (1998). "Electron Capture Dissociation of Multiply Charged Protein Cations - a Nonergodic Process". J. Am. Chem. Soc. 120 (13): 3265–3266. doi:10.1021/ja973478k.