| Frederica Louisa of Hesse-Darmstadt | |
|---|---|
 Portrait by Joseph Fredrich Darbes, 1788 | |
| Queen consort of Prussia Electress consort of Brandenburg | |
| Tenure | 17 August 1786 – 16 November 1797 |
| Born | 16 October 1751 Prenzlau, Electorate of Brandenburg, Holy Roman Empire |
| Died | 25 February 1805 (aged 53) Schloss Montbijou, Berlin, Kingdom of Prussia, Holy Roman Empire |
| Spouse | |
| Issue | Frederick William III Prince Louis Wilhelmina, Queen of the Netherlands Augusta, Electress of Hesse Prince Henry Prince Wilhelm |
| House | Hesse-Darmstadt |
| Father | Louis IX, Landgrave of Hesse-Darmstadt |
| Mother | Countess Palatine Caroline of Zweibrücken |
Frederica Louisa of Hesse-Darmstadt (German: Friederike Luise; 16 October 1751 – 25 February 1805) was Queen of Prussia and Electress of Brandenburg as the second wife of King Frederick William II.