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| Frederick of Anhalt-Harzgerode | |
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| Born | 16 November 1613 Ensdorf, Bavaria |
| Died | 30 June 1670 (aged 56) Plötzkau |
| Spouse | Johanna Elisabeth of Nassau-Hadamar Anna Katharina of Lippe-Detmold |
| House | House of Ascania |
| Father | Christian I, Prince of Anhalt-Bernburg |
| Mother | Anna of Bentheim-Tecklenburg |
Frederick of Anhalt-Harzgerode (16 November 1613, Ensdorf, Bavaria – 30 June 1670, Plötzkau), was a German prince of the House of Ascania and the first ruler of the principality of Anhalt-Harzgerode.
He was the fourth (but third surviving son) of Christian I, Prince of Anhalt-Bernburg, by his wife Anna of Bentheim-Tecklenburg, daughter of Arnold III, Count of Bentheim-Steinfurt-Tecklenburg-Limburg. In fact, he was the youngest son of his parents who survived into adulthood: his younger brother, Frederick Louis, born in 1619, died in infancy.