| Fructokinase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Fructokinase dimer, Bacillus subtilis | |||||||||
| Identifiers | |||||||||
| EC no. | 2.7.1.4 | ||||||||
| CAS no. | 9030-51-7 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Fructokinase (/fruc•to•ki•nase/ [-ki´nas]), also known as D-fructokinase or D-fructose (D-mannose) kinase,[1] is an enzyme (EC 2.7.1.4) of the liver, intestine, and kidney cortex. Fructokinase is in a family of enzymes called transferases, meaning that this enzyme transfers functional groups; it is also considered a phosphotransferase (or, frequently, a kinase) since it specifically transfers a phosphate group.[1] Fructokinase specifically catalyzes the transfer of a phosphate group from adenosine triphosphate (ATP, the substrate) to fructose as the initial step in its utilization.[1] The main role of fructokinase is in carbohydrate metabolism, more specifically, sucrose and fructose metabolism. The reaction equation is as follows:
- ATP + D-fructose → ADP + D-fructose 1-phosphate.
- ^ a b c DBGET ENZYME: 2.7.1.4 Archived 27 September 2007 at the Wayback Machine. Retrieved 2007-05-06