FtsZ

Cell division protein FtsZ
Identifiers
SymbolFtsZ
InterProIPR000158
CATH1fsz
SCOP21fsz / SCOPe / SUPFAM
CDDcd02201
FtsZ, C-terminal sandwich
Identifiers
SymbolFtsZ_C
PfamPF12327
InterProIPR024757
Available protein structures:
Pfam  structures / ECOD  
PDBRCSB PDB; PDBe; PDBj
PDBsumstructure summary
Cell division protein FtsZ
Molecular Structure of FtsZ (PDB 1fsz).
Identifiers
OrganismEscherichia coli
SymbolftsZ
UniProtP0A9A6
Search for
StructuresSwiss-model
DomainsInterPro

FtsZ is a protein encoded by the ftsZ gene that assembles into a ring at the future site of bacterial cell division (also called the Z ring). FtsZ is a prokaryotic homologue of the eukaryotic protein tubulin. The initials FtsZ mean "Filamenting temperature-sensitive mutant Z." The hypothesis was that cell division mutants of E. coli would grow as filaments due to the inability of the daughter cells to separate from one another. FtsZ is found in almost all bacteria, many archaea, all chloroplasts and some mitochondria, where it is essential for cell division. FtsZ assembles the cytoskeletal scaffold of the Z ring that, along with additional proteins, constricts to divide the cell in two.