Fukuyama coupling

Fukuyama coupling
Named after Tohru Fukuyama
Reaction type Coupling reaction
Identifiers
Organic Chemistry Portal fukuyama-coupling

The Fukuyama coupling is a coupling reaction taking place between a thioester and an organozinc halide in the presence of a palladium catalyst. The reaction product is a ketone. This reaction was discovered by Tohru Fukuyama et al. in 1998.[1]

  1. ^ Tokuyama, Hidetoshi; Yokoshima, Satoshi; Yamashita, Tohru; Fukuyama, Tohru (1998-05-14). "A novel ketone synthesis by a palladium-catalyzed reaction of thiol esters and organozinc reagents". Tetrahedron Letters. 39 (20): 3189–3192. doi:10.1016/S0040-4039(98)00456-0. ISSN 0040-4039.