G6PC3

G6PC3
Identifiers
Aliases	G6PC3, SCN4, UGRP, glucose 6 phosphatase catalytic subunit 3, glucose-6-phosphatase catalytic subunit 3
External IDs	OMIM: 611045; MGI: 1915651; HomoloGene: 16304; GeneCards: G6PC3; OMA:G6PC3 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	44,082,151 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	102,084,907 bp
RNA expression pattern
	Top expressed in
	anterior pituitary; ; right adrenal gland; ; right adrenal cortex; ; left adrenal gland; ; left adrenal cortex; ; C1 segment; ; right lobe of thyroid gland; ; stromal cell of endometrium; ; left lobe of thyroid gland; ; apex of heart;
	Top expressed in
	choroid plexus of fourth ventricle; ; spermatocyte; ; muscle of thigh; ; right kidney; ; seminiferous tubule; ; spermatid; ; yolk sac; ; entorhinal cortex; ; primary visual cortex; ; genital tubercle;
	More reference expression data
	n/a
Gene ontology
Molecular function	hydrolase activity; glucose-6-phosphatase activity;
Cellular component	integral component of membrane; integral component of endoplasmic reticulum membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum;
Biological process	phosphate-containing compound metabolic process; glucose 6-phosphate metabolic process; glucose-6-phosphate transport; dephosphorylation; gluconeogenesis;
	Sources:Amigo / QuickGO
Orthologs
	92579
	68401
	ENSG00000141349
	ENSMUSG00000034793
	Q9BUM1
	Q6NSQ9
NM_138387; NM_001319945; NM_001384165; NM_001384166; NM_001384167;
	NM_001384168
	NM_175935
NP_001306874; NP_612396; NP_001371094; NP_001371095; NP_001371096;
	NP_001371097
	NP_787949
	Wikidata
View/Edit Human	View/Edit Mouse

Glucose-6-phosphatase 3, also known as glucose-6-phosphatase beta, is an enzyme that in humans is encoded by the G6PC3 gene.^[5]^[6]^[7]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000141349 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000034793 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: glucose 6 phosphatase".
^ Martin CC, Oeser JK, Svitek CA, Hunter SI, Hutton JC, O'Brien RM (October 2002). "Identification and characterization of a human cDNA and gene encoding a ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein". Journal of Molecular Endocrinology. 29 (2): 205–22. doi:10.1677/jme.0.0290205. PMID 12370122.
^ Guionie O, Clottes E, Stafford K, Burchell A (September 2003). "Identification and characterisation of a new human glucose-6-phosphatase isoform". FEBS Letters. 551 (1–3): 159–64. doi:10.1016/S0014-5793(03)00903-7. PMID 12965222. S2CID 38286129.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000141349 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000034793 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: glucose 6 phosphatase".

[pmid12370122-6] Martin CC, Oeser JK, Svitek CA, Hunter SI, Hutton JC, O'Brien RM (October 2002). "Identification and characterization of a human cDNA and gene encoding a ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein". Journal of Molecular Endocrinology. 29 (2): 205–22. doi:10.1677/jme.0.0290205. PMID 12370122.

[pmid12965222-7] Guionie O, Clottes E, Stafford K, Burchell A (September 2003). "Identification and characterisation of a new human glucose-6-phosphatase isoform". FEBS Letters. 551 (1–3): 159–64. doi:10.1016/S0014-5793(03)00903-7. PMID 12965222. S2CID 38286129.

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