GABRA3

GABRA3
Identifiers
Aliases	GABRA3, gamma-aminobutyric acid type A receptor alpha3 subunit, gamma-aminobutyric acid type A receptor subunit alpha3
External IDs	OMIM: 305660; MGI: 95615; HomoloGene: 20218; GeneCards: GABRA3; OMA:GABRA3 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	152,451,315 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	71,700,454 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; cingulate gyrus; ; testicle; ; anterior cingulate cortex; ; Brodmann area 9; ; right frontal lobe; ; ventricular zone; ; ganglionic eminence; ; hypothalamus; ; amygdala;
	Top expressed in
	anterior amygdaloid area; ; lateral hypothalamus; ; dorsomedial hypothalamic nucleus; ; ventromedial nucleus; ; superior frontal gyrus; ; subiculum; ; lateral septal nucleus; ; medial dorsal nucleus; ; paraventricular nucleus of hypothalamus; ; lumbar subsegment of spinal cord;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	GABA-A receptor activity; ion channel activity; protein binding; benzodiazepine receptor activity; chloride channel activity; extracellular ligand-gated ion channel activity; transmembrane signaling receptor activity; inhibitory extracellular ligand-gated ion channel activity; GABA-gated chloride ion channel activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	integral component of membrane; GABA-A receptor complex; postsynaptic membrane; membrane; plasma membrane; synapse; integral component of plasma membrane; chloride channel complex; cell junction; GABA-ergic synapse; integral component of postsynaptic specialization membrane; dendrite membrane; neuron projection; postsynapse;
Biological process	gamma-aminobutyric acid signaling pathway; chloride transmembrane transport; ion transport; chloride transport; ion transmembrane transport; signal transduction; chemical synaptic transmission; regulation of membrane potential; nervous system process; synaptic transmission, GABAergic; regulation of postsynaptic membrane potential;
	Sources:Amigo / QuickGO
Orthologs
	2556
	14396
	ENSG00000011677
	ENSMUSG00000031343
	P34903
	P26049
	NM_000808
	NM_008067; NM_001357814; NM_001357815; NM_001357816; NM_001358103
	NP_000799
	NP_032093; NP_001344743; NP_001344744; NP_001344745; NP_001345032
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-aminobutyric acid receptor subunit alpha-3 is a protein that in humans is encoded by the GABRA3 gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000011677 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031343 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000011677 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031343 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: GABRA3 gamma-aminobutyric acid (GABA) A receptor, alpha 3".

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