| Pegivirus C | |
|---|---|
Virus classification 
| |
| (unranked): | Virus |
| Realm: | Riboviria |
| Kingdom: | Orthornavirae |
| Phylum: | Kitrinoviricota |
| Class: | Flasuviricetes |
| Order: | Amarillovirales |
| Family: | Flaviviridae |
| Genus: | Pegivirus |
| Species: | Pegivirus C
|
GB virus C (GBV-C), formerly known as hepatitis G virus (HGV) and also known as human pegivirus – HPgV is a virus in the family Flaviviridae and a member of the Pegivirus,[1] is known to infect humans, but is not known to cause human disease. Reportedly, HIV patients coinfected with GBV-C can survive longer than those without GBV-C, but the patients may be different in other ways. Research is active into the virus' effects on the immune system in patients coinfected with GBV-C and HIV.[2][3][4]
- ^ Stapleton, J. T.; Foung, S.; Muerhoff, A. S.; Bukh, J.; Simmonds, P. (2010). "The GB viruses: A review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae". Journal of General Virology. 92 (2): 233–46. doi:10.1099/vir.0.027490-0. PMC 3081076. PMID 21084497.
- ^ Xiang J, George SL, Wünschmann S, et al. (2004). "Inhibition of HIV-1 replication by GB virus C infection through increases in RANTES, MIP-1alpha, MIP-1beta, and SDF-1". Lancet. 363 (9426): 2040–6. doi:10.1016/S0140-6736(04)16453-2. PMID 15207954. S2CID 54317667.
- ^ Mosam A, Sathar MA, Dawood H, Cassol E, Esterhuizen TM, Coovadia HM (2007). "Effect of GB Virus C Co-infection on Response to Generic HAART in African Patients with HIV-1 Clade C Infection". AIDS. 21 (10): 1377–9. doi:10.1097/QAD.0b013e3281532cb8. PMID 17545721. S2CID 19630054.
- ^ Jung S, Eichenmüller M, Donhauser N, et al. (2007). "HIV Entry Inhibition by the Envelope 2 Glycoprotein of GB Virus C". AIDS. 21 (5): 645–7. doi:10.1097/QAD.0b013e32803277c7. PMID 17314528. S2CID 45809720.