In bioinformatics , GENSCAN is a program to identify complete gene structures in genomic DNA . It is a GHMM -based program that can be used to predict the location of genes and their exon -intron boundaries in genomic sequences from a variety of organisms. The GENSCAN Web server can be found at MIT .[ 1]
GENSCAN was developed by Christopher Burge in the research group of Samuel Karlin at Stanford University .[ 2] [ 3] [ 4]
^ http://genes.mit.edu/GENSCAN.html Archived 2013-09-06 at the Wayback Machine The GENSCAN Web Server at MIT^ Burge, C. B. (1998) Modeling dependencies in pre-mRNA splicing signals. In Salzberg, S. , Searls, D. and Kasif, S., eds. Computational Methods in Molecular Biology, Elsevier Science, Amsterdam, pp. 127-163. ISBN 978-0-444-50204-9
^ Burge, Christopher ; Karlin, Samuel (1997). "Prediction of complete gene structures in human genomic DNA" (PDF) . Journal of Molecular Biology . 268 (1): 78–94. CiteSeerX 10.1.1.115.3107 doi :10.1006/jmbi.1997.0951 . PMID 9149143 . Archived from the original (PDF) on 2015-06-20.^ Burge, C. ; Karlin, S. (1998). "Finding the genes in genomic DNA" . Current Opinion in Structural Biology . 8 (3): 346–354. doi :10.1016/S0959-440X(98)80069-9 PMID 9666331 .