GHB receptor

SLC52A2
Identifiers
Aliases	SLC52A2, BVVLS2, D15Ertd747e, GPCR41, GPR172A, PAR1, RFT3, RFVT2, hRFT3, solute carrier family 52 member 2, GHB receptor, GHBh1
External IDs	OMIM: 607882; MGI: 1289288; HomoloGene: 56994; GeneCards: SLC52A2; OMA:SLC52A2 - orthologs
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q24.3 Start 144,333,957 bp[1] End 144,361,286 bp[1]
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in mucosa of transverse colon stromal cell of endometrium right hemisphere of cerebellum granulocyte apex of heart gonad body of stomach body of pancreas spleen left adrenal cortex n/a More reference expression data BioGPS n/a
Gene ontology Molecular function protein binding virus receptor activity riboflavin transmembrane transporter activity Cellular component integral component of membrane membrane integral component of plasma membrane plasma membrane Biological process viral entry into host cell riboflavin transport riboflavin metabolic process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 79581 52710 Ensembl ENSG00000185803 ENSG00000285112 n/a UniProt Q9HAB3 Q9D8F3 RefSeq (mRNA) NM_001253815 NM_001253816 NM_024531 NM_001363118 NM_001363120 NM_001363121 NM_001363122 NM_029643 RefSeq (protein) NP_001240744 NP_001240745 NP_078807 NP_001350047 NP_001350049 NP_001350050 NP_001350051 NP_083919 Location (UCSC) Chr 8: 144.33 – 144.36 Mb n/a PubMed search [2] [3]
Wikidata
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The γ-hydroxybutyrate (GHB) receptor (GHBR), originally identified as GPR172A, is an excitatory G protein-coupled receptor (GPCR) that binds the neurotransmitter and psychoactive drug γ-hydroxybutyric acid (GHB). As solute carrier family 52 member 2 (SLC52A2), it is also a transporter for riboflavin.