GLIMMER

GLIMMER
Developer(s)Steven Salzberg & Arthur Delcher
Stable release
3.02 / 9 May 2006 (2006-05-09)
Available inC++
TypeBioinformatics tool
LicenseOSI Certified Open Source Software under the Artistic License
Websiteccb.jhu.edu/software/glimmer/index.shtml

In bioinformatics, GLIMMER (Gene Locator and Interpolated Markov ModelER) is used to find genes in prokaryotic DNA.[1] "It is effective at finding genes in bacteria, archea, viruses, typically finding 98-99% of all relatively long protein coding genes".[1] GLIMMER was the first system that used the interpolated Markov model[2] to identify coding regions. The GLIMMER software is open source and is maintained by Steven Salzberg, Art Delcher, and their colleagues at the Center for Computational Biology[3] at Johns Hopkins University. The original GLIMMER algorithms and software were designed by Art Delcher, Simon Kasif and Steven Salzberg and applied to bacterial genome annotation in collaboration with Owen White.

  1. ^ a b Salzberg, S. L.; Delcher, A. L.; Kasif, S.; White, O. (1998). "Microbial gene identification using interpolated Markov models". Nucleic Acids Research. 26 (2): 544–548. doi:10.1093/nar/26.2.544. PMC 147303. PMID 9421513.
  2. ^ Salzberg, S. L.; Pertea, M.; Delcher, A. L.; Gardner, M. J.; Tettelin, H. (1999). "Interpolated Markov Models for Eukaryotic Gene Finding". Genomics. 59 (1): 24–31. CiteSeerX 10.1.1.126.431. doi:10.1006/geno.1999.5854. PMID 10395796.
  3. ^ "Center for Computational Biology". Johns Hopkins University. Retrieved 23 March 2013.