GNAT3

GNAT3
Identifiers
Aliases	GNAT3, GDCA, G protein subunit alpha transducin 3, HG1E
External IDs	OMIM: 139395; MGI: 3588268; HomoloGene: 24284; GeneCards: GNAT3; OMA:GNAT3 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	80,512,064 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	18,224,832 bp
RNA expression pattern
	Top expressed in
	testicle; ; gonad; ; tibialis anterior muscle; ; duodenum; ; abdominal wall; ; mucosa of small intestine; ; prefrontal cortex; ; right lobe of thyroid gland; ; left lobe of thyroid gland; ; large intestine;
	Top expressed in
	mucosa of large intestine; ; intestinal epithelium; ; tongue; ; epithelium of colon; ; mucosa of small intestine; ; neural layer of retina; ; vallate papilla; ; secondary oocyte; ; epithelium of small intestine; ; white adipose tissue;
	More reference expression data
	n/a
Gene ontology
Molecular function	signal transducer activity; metal ion binding; nucleotide binding; guanyl nucleotide binding; G protein-coupled receptor binding; G-protein beta/gamma-subunit complex binding; GTP binding; GTPase activity;
Cellular component	acrosomal vesicle; cytoplasm; axoneme; heterotrimeric G-protein complex; apical plasma membrane; plasma membrane; photoreceptor outer segment; photoreceptor inner segment; protein-containing complex;
Biological process	signal transduction; sensory perception of umami taste; response to nicotine; adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; sensory perception of bitter taste; sensory perception of taste; sensory perception of sweet taste; protein folding; detection of chemical stimulus involved in sensory perception of bitter taste; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	346562
	242851
	ENSG00000214415
	ENSMUSG00000028777
	A8MTJ3
	Q3V3I2
	NM_001102386
	NM_001081143
	NP_001095856
	NP_001074612
	Wikidata
View/Edit Human	View/Edit Mouse

Guanine nucleotide-binding protein G(t) subunit alpha-3, also known as gustducin alpha-3 chain, is a protein subunit that in humans is encoded by the GNAT3 gene.^[5]

Gustducin alpha-3 chain is a subunit of the heterotrimeric G protein gustducin that is responsible for basic taste.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000214415 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000028777 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: guanine nucleotide binding protein".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000214415 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000028777 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: guanine nucleotide binding protein".

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