GPR119

GPR119
Identifiers
AliasesGPR119, GPCR2, G protein-coupled receptor 119
External IDsOMIM: 300513; MGI: 2668412; HomoloGene: 18670; GeneCards: GPR119; OMA:GPR119 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_178471

NM_181751

RefSeq (protein)

NP_848566

NP_861416

Location (UCSC)Chr X: 130.38 – 130.39 MbChr X: 47.76 – 47.76 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

G protein-coupled receptor 119 also known as GPR119 is a G protein-coupled receptor that in humans is encoded by the GPR119 gene.[5]

GPR119, along with GPR55 and GPR18, have been implicated as novel cannabinoid receptors.[6][7][8]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000147262Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000051209Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: GPR119 G protein-coupled receptor 119".
  6. ^ Brown AJ (November 2007). "Novel cannabinoid receptors". British Journal of Pharmacology. 152 (5): 567–575. doi:10.1038/sj.bjp.0707481. PMC 2190013. PMID 17906678.
  7. ^ Izzo AA, Sharkey KA (April 2010). "Cannabinoids and the gut: new developments and emerging concepts". Pharmacology & Therapeutics. 126 (1): 21–38. doi:10.1016/j.pharmthera.2009.12.005. PMID 20117132.
  8. ^ McHugh D, Hu SS, Rimmerman N, Juknat A, Vogel Z, Walker JM, Bradshaw HB (March 2010). "N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor". BMC Neuroscience. 11: 44. doi:10.1186/1471-2202-11-44. PMC 2865488. PMID 20346144.