GPR65

GPR65
Identifiers
Aliases	GPR65, TDAG8, hTDAG8, G protein-coupled receptor 65
External IDs	OMIM: 604620; MGI: 108031; HomoloGene: 2675; GeneCards: GPR65; OMA:GPR65 - orthologs
Gene location (Human)
Chr.	Chromosome 14 (human)
End	88,014,811 bp
Gene location (Mouse)
Chr.	Chromosome 12 (mouse)
End	98,242,903 bp
RNA expression pattern
	Top expressed in
	white blood cell; ; mononuclear cell; ; monocyte; ; periodontal fiber; ; granulocyte; ; blood; ; bone marrow; ; appendix; ; trabecular bone; ; spleen;
	Top expressed in
	granulocyte; ; stroma of bone marrow; ; spleen; ; lymph node; ; thymus; ; mesenteric lymph nodes; ; blood; ; dermis; ; pharynx; ; subcutaneous adipose tissue;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; integral component of plasma membrane; membrane; intracellular anatomical structure;
Biological process	multicellular organism development; actin cytoskeleton reorganization; immune response; positive regulation of stress fiber assembly; activation of GTPase activity; response to acidic pH; signal transduction; apoptotic process; positive regulation of Rho protein signal transduction; positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway; G protein-coupled receptor signaling pathway; adenylate cyclase-activating G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	8477
	14744
	ENSG00000140030
	ENSMUSG00000021886
	Q8IYL9
	Q61038
	NM_003608
	NM_008152
	NP_003599
	NP_032178
	Wikidata
View/Edit Human	View/Edit Mouse

Psychosine receptor is a G protein-coupled receptor (GPCR) protein that in humans is encoded by the GPR65 gene.^[5]^[6] GPR65 is also referred to as TDAG8.

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000140030 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000021886 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Kyaw H, Zeng Z, Su K, Fan P, Shell BK, Carter KC, Li Y (June 1998). "Cloning, characterization, and mapping of human homolog of mouse T-cell death-associated gene". DNA and Cell Biology. 17 (6): 493–500. doi:10.1089/dna.1998.17.493. PMID 9655242.
^ "Entrez Gene: GPR65 G protein-coupled receptor 65".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000140030 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000021886 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9655242-5] Kyaw H, Zeng Z, Su K, Fan P, Shell BK, Carter KC, Li Y (June 1998). "Cloning, characterization, and mapping of human homolog of mouse T-cell death-associated gene". DNA and Cell Biology. 17 (6): 493–500. doi:10.1089/dna.1998.17.493. PMID 9655242.

[entrez-6] "Entrez Gene: GPR65 G protein-coupled receptor 65".

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