GSTO2

GSTO2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3Q18, 3Q19, 3QAG
Identifiers
Aliases	GSTO2, GSTO 2-2, bA127L20.1, glutathione S-transferase omega 2
External IDs	OMIM: 612314; MGI: 1915464; HomoloGene: 57057; GeneCards: GSTO2; OMA:GSTO2 - orthologs
EC number	1.8.5.1
Gene location (Human)
Chr.	Chromosome 10 (human)
End	104,304,950 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	47,874,763 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; skin of arm; ; islet of Langerhans; ; skin of abdomen; ; right testis; ; right uterine tube; ; left testis; ; skin of leg; ; anterior pituitary; ; pancreatic ductal cell;
	Top expressed in
	spermatid; ; spermatocyte; ; seminiferous tubule; ; hair; ; morula; ; embryo; ; embryo; ; thyroid gland; ; brown adipose tissue; ; transitional epithelium of urinary bladder;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; oxidoreductase activity; methylarsonate reductase activity; protein binding; glutathione dehydrogenase (ascorbate) activity; identical protein binding; glutathione transferase activity;
Cellular component	cytosol; extracellular exosome; cytoplasm;
Biological process	metabolism; cellular response to arsenic-containing substance; glutathione derivative biosynthetic process; L-ascorbic acid metabolic process; xenobiotic metabolic process; cellular oxidant detoxification; glutathione metabolic process; toxin catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	119391
	68214
	ENSG00000065621
	ENSMUSG00000025069
	Q9H4Y5
	Q8K2Q2
	NM_001191013; NM_001191014; NM_001191015; NM_183239
	NM_026619; NM_030051
	NP_001177942; NP_001177943; NP_001177944; NP_899062
	NP_080895; NP_084327
	Wikidata
View/Edit Human	View/Edit Mouse

Glutathione S-transferase omega-2 is an enzyme that in humans is encoded by the GSTO2 gene.^[5]^[6]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000065621 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025069 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Whitbread AK, Tetlow N, Eyre HJ, Sutherland GR, Board PG (Mar 2003). "Characterization of the human Omega class glutathione transferase genes and associated polymorphisms". Pharmacogenetics. 13 (3): 131–44. doi:10.1097/00008571-200303000-00003. PMID 12618591.
^ "Entrez Gene: GSTO2 glutathione S-transferase omega 2".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000065621 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000025069 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12618591-5] Whitbread AK, Tetlow N, Eyre HJ, Sutherland GR, Board PG (Mar 2003). "Characterization of the human Omega class glutathione transferase genes and associated polymorphisms". Pharmacogenetics. 13 (3): 131–44. doi:10.1097/00008571-200303000-00003. PMID 12618591.

[entrez-6] "Entrez Gene: GSTO2 glutathione S-transferase omega 2".

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