GUCY2D

GUCY2D
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1AWL
Identifiers
Aliases	GUCY2D, CORD5, CORD6, CYGD, GUC1A4, GUC2D, LCA, LCA1, RCD2, RETGC-1, ROS-GC1, ROSGC, retGC, guanylate cyclase 2D, retinal, CACD1, CSNB1I, CG-E
External IDs	OMIM: 600179; MGI: 105123; HomoloGene: 55442; GeneCards: GUCY2D; OMA:GUCY2D - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	8,020,342 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	69,127,862 bp
RNA expression pattern
	Top expressed in
	mucosa of esophagus; ; white blood cell; ; monocyte; ; minor salivary glands; ; granulocyte; ; vagina; ; right lung; ; lymph node; ; prostate; ; primary visual cortex;
	Top expressed in
	neural layer of retina; ; secondary oocyte; ; zygote; ; morula; ; embryo; ; primary oocyte; ; dentate gyrus of hippocampal formation granule cell; ; outer nuclear layer; ; primary visual cortex; ; blastocyst;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein kinase activity; nucleotide binding; GTP binding; protein binding; lyase activity; phosphorus-oxygen lyase activity; ATP binding; guanylate cyclase activity; signaling receptor activity; adenylate cyclase activity; peptide receptor activity;
Cellular component	integral component of membrane; membrane; integral component of plasma membrane; photoreceptor disc membrane; guanylate cyclase complex, soluble; nuclear outer membrane; plasma membrane;
Biological process	intracellular signal transduction; response to stimulus; regulation of rhodopsin mediated signaling pathway; cyclic nucleotide biosynthetic process; receptor guanylyl cyclase signaling pathway; protein phosphorylation; visual perception; cGMP biosynthetic process; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	3000
	14919
	ENSG00000132518
	ENSMUSG00000020890
	Q02846
	P52785
	NM_000180
	NM_008192
	NP_000171
	NP_032218
	Wikidata
View/Edit Human	View/Edit Mouse

Retinal guanylyl cyclase 1 also known as guanylate cyclase 2D, retinal is an enzyme that in humans is encoded by the GUCY2D (guanylate cyclase 2D) gene.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132518 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000020890 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Guanylate cyclase 2D, membrane (retina-specific)".

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000132518 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000020890 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Guanylate cyclase 2D, membrane (retina-specific)".

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