Gamithromycin

Gamithromycin
Clinical data
Trade namesZactran
Other namesML-1709460, ML-460
License data
Routes of
administration		Subcutaneous
Drug classMacrolide antibiotic
ATCvet code
Legal status
Legal status
Identifiers
  • (2R,3S,4R,5S,8R,10R,11R,12S,13S,14R)-11-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}-2-ethyl-3,4,10-trihydroxy-13-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}-3,5,8,10,12,14-hexamethyl-7-propyl-1-oxa-7-azacyclopentadecan-15-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.123.704 Edit this at Wikidata
Chemical and physical data
FormulaC40H76N2O12
Molar mass777.050 g·mol−1
3D model (JSmol)
  • [H][C@@]1(C[C@@](C)(OC)[C@@H](O)[C@H](C)O1)O[C@H]1[C@H](C)[C@@H](O[C@]2([H])O[C@H](C)C[C@@H]([C@H]2O)N(C)C)[C@](C)(O)C[C@@H](C)N(CCC)C[C@H](C)[C@@H](O)[C@](C)(O)[C@@H](CC)OC(=O)[C@@H]1C
  • InChI=1S/C40H76N2O12/c1-15-17-42-21-22(3)33(44)40(11,48)29(16-2)52-36(46)26(7)32(53-30-20-39(10,49-14)34(45)27(8)51-30)25(6)35(38(9,47)19-23(42)4)54-37-31(43)28(41(12)13)18-24(5)50-37/h22-35,37,43-45,47-48H,15-21H2,1-14H3/t22-,23+,24+,25-,26+,27-,28-,29+,30-,31+,32-,33+,34-,35+,37-,38+,39+,40+/m0/s1
  • Key:VWAMTBXLZPEDQO-UZSBJOJWSA-N

Gamithromycin, sold under the brand name Zactran, is a veterinary medication used for the treatment of cattle, pigs, and sheep.[3][4][5] It is a macrolide antibacterial.[3][4] It is a 7a-azalide.[6]

It was approved for veterinary use in the European Union in 2008.[3][4]

  1. ^ "Zactran - gamithromycin injection, solution". DailyMed. 17 April 2024. Retrieved 29 June 2024.
  2. ^ "Zactran". U.S. Food and Drug Administration (FDA). Retrieved 29 June 2024.
  3. ^ a b c d "Zactran EPAR". European Medicines Agency. 1 August 2008. Retrieved 29 June 2024.
  4. ^ a b c d "Zactran PI". Union Register of veterinary medicinal products. 28 July 2008. Retrieved 29 June 2024.
  5. ^ Budde JA, McCluskey DM (2023). "Gamithromycin". Plumb's Veterinary Drug Handbook (10th ed.). Tulsa, OK: Educational Concepts, LLC, dba VetMedux. p. 571. ISBN 978-1-394-17220-7.
  6. ^ "Gamithromycin". Inxight Drugs. Retrieved 29 June 2024. Public Domain This article incorporates text from this source, which is in the public domain.