Gamma-glutamyl carboxylase

GGCX
Identifiers
Aliases	GGCX, VKCFD1, gamma-glutamyl carboxylase, Gamma-glutamyl carboxylase; GGCX
External IDs	OMIM: 137167; MGI: 1927655; HomoloGene: 639; GeneCards: GGCX; OMA:GGCX - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	85,561,532 bp
RNA expression pattern
	Top expressed in
	buccal mucosa cell; ; tendon of biceps brachii; ; liver; ; right lobe of liver; ; endothelial cell; ; stromal cell of endometrium; ; internal globus pallidus; ; saphenous vein; ; body of pancreas; ; parotid gland;
	n/a
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	gamma-glutamyl carboxylase activity; lyase activity;
Cellular component	integral component of membrane; endoplasmic reticulum membrane; membrane; endoplasmic reticulum;
Biological process	peptidyl-glutamic acid carboxylation; blood coagulation;
	Sources:Amigo / QuickGO
Orthologs
	2677
	56316
	ENSG00000115486
	ENSMUSG00000053460
	P38435
	Q9QYC7
	NM_000821; NM_001142269; NM_001311312
	NM_019802
	NP_000812; NP_001135741; NP_001298241
	NP_062776
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-glutamyl carboxylase is an enzyme that in humans is encoded by the GGCX gene, located on chromosome 2 at 2p12.^[4]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000115486 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Wu SM, Cheung WF, Frazier D, Stafford DW (December 1991). "Cloning and expression of the cDNA for human gamma-glutamyl carboxylase". Science. 254 (5038): 1634–6. Bibcode:1991Sci...254.1634W. doi:10.1126/science.1749935. PMID 1749935.