Gene knockdown

Gene knockdown is an experimental technique by which the expression of one or more of an organism's genes is reduced. The reduction can occur either through genetic modification or by treatment with a reagent such as a short DNA or RNA oligonucleotide that has a sequence complementary to either gene or an mRNA transcript.[1]

  1. ^ Summerton JE (2007). "Morpholino, siRNA, and S-DNA compared: impact of structure and mechanism of action on off-target effects and sequence specificity". Current Topics in Medicinal Chemistry. 7 (7): 651–60. doi:10.2174/156802607780487740. PMID 17430206. S2CID 12241724.