| Genodermatosis | |
|---|---|
| Other names | genodermatoses |
 | |
| A patient with Clouston's hidrotic ectodermal dysplasia, one of the rare genodermatosis. | |
| Specialty | Dermatology, Medical genetics |
| Causes | Family history; gene mutation; chromosome abnormality |
Genodermatosis is a hereditary skin disease with three inherited modes including single gene inheritance, multiple gene inheritance and chromosome inheritance.[1] There are many different types of genodermatosis; the prevalence of genodermatosis ranges from 1 per 6000 people to 1 per 500,000 people.[2] Genodermatosis has influence on the texture, color and structure of skin cuticle and connective tissue, specific lesion site and clinical manifestations on the body vary depending on the type.[3] In the spite of the variety and complexity of genodermatosis, there are still some common methods that can help people diagnose.[4] After diagnosis, different types of genodermatosis require different levels of therapy including interventions, nursing interventions and treatments.[5] Among that, research of therapy for some new, complex and rare types are still in the developing stage.[6] The impact of genodermatosis not only can be seen in body but also can be seen in all aspects of patients' life, including but not limited to psychological, family life, economic conditions and social activities.[5][7] Accordingly, the patients need treatment, support and help in these areas.[5]
- ^ Babu, N. Aravindha; Rajesh, E.; Krupaa, Jayasri; Gnananandar, G. (2015). "Genodermatoses". Journal of Pharmacy & Bioallied Sciences. 7 (Suppl 1): S203–S206. doi:10.4103/0975-7406.155903. PMC 4439671. PMID 26015711.
- ^ Fields, D. (2019, June). Types of Genodermatoses. Retrieved September 08, 2020, from https://www.news-medical.net/health/Types-of-Genodermatoses.aspx
- ^ Bayart, Cheryl B.; Brandling-Bennett, Heather A. (2018). "Congenital and Hereditary Disorders of the Skin". Avery's Diseases of the Newborn. pp. 1475–1494.e1. doi:10.1016/B978-0-323-40139-5.00104-2. ISBN 978-0-323-40139-5.
- ^ Tantcheva-Poór, Iliana; Oji, Vinzenz; Has, Cristina (October 2016). "A multistep approach to the diagnosis of rare genodermatoses". Journal der Deutschen Dermatologischen Gesellschaft. 14 (10): 969–986. doi:10.1111/ddg.13140. PMID 27767270. S2CID 46823821.
- ^ a b c Fondation René Touraine. (n.d.). Genodermatoses & Rare Skin Disorders - a public health priority. Retrieved September 08, 2020, from https://www.frt-rareskin.org/Genodermatoses-Rare-Skin-Disorders
- ^ Chamcheu, Jean Christopher; Wood, Gary S.; Siddiqui, Imtiaz A.; Syed, Deeba N.; Adhami, Vaqar M.; Teng, Joyce M.; Mukhtar, Hasan (July 2012). "Progress towards genetic and pharmacological therapies for keratin genodermatoses: current perspective and future promise". Experimental Dermatology. 21 (7): 481–489. doi:10.1111/j.1600-0625.2012.01534.x. PMC 3556927. PMID 22716242.
- ^ Dufresne, H.; Hadj-Rabia, S.; Bodemer, C. (November 2018). "Impact of a rare chronic genodermatosis on family daily life: the example of epidermolysis bullosa". British Journal of Dermatology. 179 (5): 1177–1178. doi:10.1111/bjd.16710. PMID 29710387. S2CID 207077766.