Georg (20 February 1518 – 17 May 1569) was the Count Palatine of Simmern-Sponheim from 1559 until 1569.
George was born in 1518 to Johann II, Count Palatine of Simmern and Beatrix of Baden. In 1559 his elder brother Frederick inherited the Electorate of the Palatinate and gave George his old territories inherited from his father in 1557. George married Elisabeth of Hesse, daughter of Landgrave Wilhelm I, on 9 January 1541. George died in 1569 and was succeeded in Simmern by his younger brother Reichard.