George Beadle

George Beadle
Born
George Wells Beadle

(1903-10-22)October 22, 1903[2]
DiedJune 9, 1989(1989-06-09) (aged 85)
Alma materUniversity of Nebraska (BS)
Cornell University (MS, PhD)
Known for
Awards
Scientific career
FieldsGenetics
Institutions
ThesisGenetical and Cytological Studies of Mendelian Asynapsis in Zea mays (1930)
Doctoral advisor
Other academic advisors
Doctoral students
Other notable students

George Wells Beadle (October 22, 1903 – June 9, 1989) was an American geneticist. In 1958 he shared one-half of the Nobel Prize in Physiology or Medicine with Edward Tatum for their discovery of the role of genes in regulating biochemical events within cells.[3][4] He also served as the 7th President of the University of Chicago.[5]

Beadle and Tatum's key experiments involved exposing the bread mold Neurospora crassa to x-rays, causing mutations. In a series of experiments, they showed that these mutations caused changes in specific enzymes involved in metabolic pathways. These experiments led them to propose a direct link between genes and enzymatic reactions, known as the One gene-one enzyme hypothesis.[6][7][8]

  1. ^ a b c d "DevTree - George Wells Beadle". academictree.org.
  2. ^ Cite error: The named reference frs was invoked but never defined (see the help page).
  3. ^ George W. BeadleBiographical Memoirs of the National Academy of Sciences
  4. ^ Stern, C. (1954). "George W. Beadle". Science. 119 (3086): 229–230. Bibcode:1954Sci...119..229S. doi:10.1126/science.119.3086.229. PMID 13135519.
  5. ^ "George W. Beadle | Office of the President | The University of Chicago". president.uchicago.edu. 12 June 2012. Retrieved 2019-06-22.
  6. ^ Beadle, G. W.; Tatum, E. L. (1941). "Genetic Control of Biochemical Reactions in Neurospora" (PDF). Proceedings of the National Academy of Sciences. 27 (11): 499–506. Bibcode:1941PNAS...27..499B. doi:10.1073/pnas.27.11.499. PMC 1078370. PMID 16588492.
  7. ^ Paul Berg and Maxine Singer. George Beadle: An Uncommon Farmer. The Emergence of Genetics in the 20th Century. Cold Springs Harbor Laboratory Press, 2003. ISBN 0-87969-688-5
  8. ^ Key Participants: George Beadle - It's in the Blood! A Documentary History of Linus Pauling, Hemoglobin, and Sickle Cell Anemia