| George III | |
|---|---|
 | |
| Prince of Anhalt-Dessau | |
| Reign | 1516–1544 |
| Predecessor | Ernest I |
| Successor | defunct |
| Prince of Anhalt-Plötzkau | |
| Reign | 1544–1553 |
| Predecessor | Principality created |
| Successor | Karl I Bernhard VII |
| Born | 15 August 1507 Dessau |
| Died | 17 October 1553 (aged 46) Dessau |
| House | House of Ascania |
| Father | Ernest I, Prince of Anhalt-Dessau |
| Mother | Margaret of Münsterberg |
George III, Prince of Anhalt-Dessau (15 August 1507 – 17 October 1553), was a German prince of the House of Ascania and ruler of the principality of Anhalt-Dessau, and also a Protestant Reformer. After 1544 he became the first ruler of the principality of Anhalt-Plötzkau.
George was the third (but second surviving) son of Ernest I, Prince of Anhalt-Dessau, by his wife Margaret of Münsterberg, daughter of Henry I, Duke of Münsterberg-Oels and granddaughter of George of Poděbrady, King of Bohemia.