Giorgi II Gurieli (Georgian: გიორგი II გურიელი; died 1600), of the House of Gurieli, was Prince of Guria from 1564 to 1583 and again from 1587 to 1600. Succeeding on the death of his father Rostom Gurieli, Giorgi's rule over his small principality, located in southwest Georgia, was a period of conflict with the neighboring Dadiani of Mingrelia and increasing assertiveness of the Ottomans whom Gurieli submitted in 1581. His reign was interrupted, from 1583 to 1587, by a Mingrelian invasion, but Giorgi was able to resume the throne with Ottoman support.