George Meade (February 27, 1741 – November 9, 1808) was an American merchant, politician and slave trader best known for being the grandfather of Civil War general George Gordon Meade. In partnership with Thomas Fitzsimons, his firm was among the largest provision merchants during the American Revolutionary War, and helped finance the Bank of Pennsylvania and Bank of North America during the conflict—while it profited from British goods as well. Meade's business went bankrupt by 1801 due to investments in the Yazoo land scandal, and was continued by his son Richard W. Meade.
Meade held minor city offices and was active in religious and civic life, among others serving as a trustee at St. Mary's Roman Catholic Church and founding the Friendly Sons of St. Patrick. Descendants amplified these accomplishments into a legendary patriotism, though his influence has been assessed more modestly by recent biographers.