Glucagon-like peptide-2 receptor

GLP2R
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	7D68
Identifiers
Aliases	GLP2R, entrez:9340, glucagon like peptide 2 receptor
External IDs	OMIM: 603659; MGI: 2136733; HomoloGene: 3132; GeneCards: GLP2R; OMA:GLP2R - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	9,892,099 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	67,661,979 bp
RNA expression pattern
	Top expressed in
	testicle; ; epithelium of colon; ; gallbladder; ; muscle layer of sigmoid colon; ; transverse colon; ; gastric mucosa; ; rectum; ; mucosa of transverse colon; ; gonad; ; canal of the cervix;
	Top expressed in
	neural layer of retina; ; Hindgut; ; midgut; ; jejunum; ; ileum; ; colon; ; urinary bladder; ; dentate gyrus of hippocampal formation granule cell; ; duodenum; ; rectum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	G protein-coupled receptor activity; glucagon receptor activity; transmembrane signaling receptor activity; signal transducer activity; G protein-coupled peptide receptor activity; peptide hormone binding;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	cellular response to glucagon stimulus; cell surface receptor signaling pathway; positive regulation of cell population proliferation; signal transduction; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	9340
	93896
	ENSG00000065325
	ENSMUSG00000049928
	O95838
	Q5IXF8
	NM_004246
	NM_175681
	NP_004237
	NP_783612
	Wikidata
View/Edit Human	View/Edit Mouse

Glucagon-like peptide-2 receptor (GLP-2R) is a protein that in human is encoded by the GLP2R gene located on chromosome 17.^[5]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000065325 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000049928 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Brubaker PL, Drucker DJ (2002). "Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors". Receptors & Channels. 8 (3–4): 179–88. doi:10.1080/10606820213687. PMID 12529935.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000065325 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000049928 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid12529935-5] Brubaker PL, Drucker DJ (2002). "Structure-function of the glucagon receptor family of G protein-coupled receptors: the glucagon, GIP, GLP-1, and GLP-2 receptors". Receptors & Channels. 8 (3–4): 179–88. doi:10.1080/10606820213687. PMID 12529935.

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