Glucuronolactone

Glucuronolactone[1]
Skeletal formula
Space-filling model
Names
IUPAC name
D-Glucurono-6,3-lactone
Systematic IUPAC name
(2R)-2-[(2S,3R,4S)-3,4-Dihydroxy-5-oxo-tetrahydrofuran-2-yl]-2-hydroxy-acetaldehyde
Other names
Glucuronic acid lactone; Glucurone; Glucurolactone (INN); D-glucurono-gamma-lactone; glucurono-γ-lactone
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.046.397 Edit this at Wikidata
UNII
  • InChI=1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h1-5,8-10H/t2-,3+,4-,5+/m0/s1 ☒N
    Key: UYUXSRADSPPKRZ-SKNVOMKLSA-N ☒N
  • InChI=1/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h1-5,8-10H/t2-,3+,4-,5+/m0/s1
    Key: UYUXSRADSPPKRZ-SKNVOMKLBS
  • O=C[C@H](O)[C@H]1OC(=O)[C@@H](O)[C@H]1O
Properties
C6H8O6
Molar mass 176.124 g·mol−1
Density 1.76 g/cm3 (30 °C)
Melting point 176 to 178 °C (349 to 352 °F; 449 to 451 K)
26.9 g/100 mL
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Glucuronolactone or Glucurolactone (INN) is a naturally occurring substance that is an important structural component of nearly all connective tissues.[1] It is sometimes used in energy drinks.[2][3] Unfounded claims[4] that glucuronolactone can be used to reduce "brain fog"[5] are based on research conducted on energy drinks that contain other active ingredients that have been shown to improve cognitive function, such as caffeine. Glucuronolactone is also found in many plant gums.[1]

  1. ^ a b c Merck Index, 11th Edition, 4362
  2. ^ "V Energy". v.co.nz. Retrieved 2021-07-22.
  3. ^ Rahnama, Nader; Gaeini, Abbas Ali; Kazemi, Fahimeh (2010). "The effectiveness of two energy drinks on selected indices of maximal cardiorespiratory fitness and blood lactate levels in male athletes". Journal of Research in Medical Sciences. 15 (3): 127–132. ISSN 1735-1995. PMC 3082800. PMID 21526071.
  4. ^ "Does Glucuronolactone Boost Energy? Benefits vs. Dangers". SelfHacked. 2019-12-05. Retrieved 2020-10-23.
  5. ^ "Glucuronolactone Benefits & Safety in Red Bull Energy Drinks". Nootriment - Health Supplement Reviews and Research. 2015-12-10. Retrieved 2021-07-22.