Goodbye (Grey's Anatomy)

"Goodbye" is the second episode of the sixth season of the American television medical drama Grey's Anatomy, and the show's 104th episode overall. Written by Krista Vernoff and directed by Bill D'Elia, the episode was originally broadcast on the American Broadcasting Company (ABC) in the United States on September 24, 2009.

In the episode, the doctors of Seattle Grace Hospital come to terms with the death of their colleague George O'Malley (T. R. Knight). Additional storylines include Richard Webber (James Pickens, Jr.) being involved in a car accident, Callie Torres (Sara Ramirez) receiving a job offer as an attending physician at a nearby hospital, and Alex Karev (Justin Chambers) struggling with his marriage to Izzie Stevens (Katherine Heigl) following her near-death experience.

Although the episode was fictionally set in Seattle, Washington, filming took place in Los Angeles, California. The episode is the second part of the two-hour season premiere, the first part being "Good Mourning". It marks the first episode without Knight following his departure from the series and the first to feature Jessica Capshaw (Arizona Robbins) as a series regular. Guest stars included Shannon Lucio, Amy Madigan, Martha Plimpton, Zack Shada, Mitch Pileggi, and Zoe Boyle.

Upon its original broadcast, "Goodbye" was viewed by 17.03 million people in the United States, ranking #1 for the night, and garnered a 6.7/17 Nielsen rating/share in the 18–49 demographic. The episode received positive reviews from television critics, with high praise for the performances of Ramirez and Chyler Leigh (Lexie Grey).