| Goya Award for Best Actress | |
|---|---|
 The 2024 recipient: Malena Alterio | |
| Awarded for | Best Performance by an Actress in a Leading Role |
| Country | Spain |
| Presented by | Academy of Cinematographic Arts and Sciences of Spain (AACCE) |
| First awarded | 1987 (for performance in films released during the 1986 film season) |
| Most recent winner | Malena Alterio Something Is About to Happen (2023) |
The Goya Award for Best Actress (Spanish: Premio Goya a la mejor interpretación femenina protagonista) is one of the Goya Awards, Spain's principal national film awards.
Since its inception, the award has been given to 26 actresses. At the 1st Goya Awards ceremony held in 1987, Amparo Rivelles was the first winner of this award for her role as Laura in We Must Undo the House. Carmen Maura has received the most awards in this category with three wins. Penélope Cruz was nominated on twelve occasions, winning two times.
As of the 2024 ceremony, Malena Alterio is the most recent winner in this category for her role as Lucía in Something Is About to Happen.