Granulicatella adiacens

Granulicatella adiacens
Scientific classification Edit this classification
Domain: Bacteria
Phylum: Bacillota
Class: Bacilli
Order: Lactobacillales
Family: Carnobacteriaceae
Genus: Granulicatella
Species:
G. adiacens
Binomial name
Granulicatella adiacens
Collins & Lawson, 2000[1]

Granulicatella adiacens is a fastidious Gram-positive cocci (pairs, chains) and is part of the nutritionally variant streptococci (NVS).[2][3][4] Like other constituents of the NVS, it can cause bacteremia and infective endocarditis (IE), with significant morbidity and mortality.[4][2] NVS has less often been implicated in a variety of other infections, including those of the orbit, nasolacrimal duct and breast implants.[5] It is a commensal of the human mouth, genital, and intestinal tracts, although it is rarely implicated in infections,[5][2] in part due to it being a fastidious organism and rarely being identified in the laboratory environment.[5] However, its identification has become more frequent with use of commercial mediums and automated identification systems.[5] Because it has been difficult to identify, it has been considered one of the causes of culture negative IE.[2] Identifying G. adiacens can allow more appropriate selection of antibiotics, especially when susceptibility testing is not available.[4]

  1. ^ Collins, MD; Lawson, PA (January 2000). "The genus Abiotrophia (Kawamura et al.) is not monophyletic: proposal of Granulicatella gen. nov., Granulicatella adiacens comb. nov., Granulicatella elegans comb. nov. and Granulicatella balaenopterae comb. nov". International Journal of Systematic and Evolutionary Microbiology. 50 Pt 1: 365–369. doi:10.1099/00207713-50-1-365. PMID 10826824.
  2. ^ a b c d Shailaja, TS; Sathiavathy, KA; Unni, Unni (July 2013). "Infective endocarditis caused by Granulicatella adiacens". Indian Heart Journal. 65 (4): 447–9. doi:10.1016/j.ihj.2013.06.014. PMC 3861137. PMID 23993006.
  3. ^ Cite error: The named reference Gardenier2011bacteremiaCase was invoked but never defined (see the help page).
  4. ^ a b c Alberti, Michael O.; Hindler, Janet A.; Humphreys, Romeny M. (26 February 2016). "Antimicrobial Susceptibilities of Abiotrophia defectiva, Granulicatella adiacens, and Granulicatella elegans". Antimicrobial Agents and Chemotherapy. 60 (3): 1411–1420. doi:10.1128/AAC.02645-15. PMC 4776019. PMID 26666926.
  5. ^ a b c d Gupta, Sangita; Garg, Meenu; Misra, Sanjay; Singhal, Sanjay (Jan–Mar 2018). "Granulicatella adiacens abscess: Two rare cases and review". Journal of Laboratory Physicians. 10 (1): 121–123. doi:10.4103/JLP.JLP_58_17. PMC 5784284. PMID 29403221.