The Great New Orleans Fire (1788) (Spanish: Gran Incendio de Nueva Orleans, French: Grand incendie de La Nouvelle-Orléans) was a fire that destroyed 856 of the 1,100 structures in New Orleans, Louisiana (New Spain), on March 21, 1788, spanning the south central Vieux Carré from Burgundy to Chartres Street, almost to the Mississippi River front buildings. An additional 212 buildings were destroyed in a later citywide fire on December 8, 1794.