Gregg L. Semenza

Gregg L. Semenza
Semenza in Stockholm, December, 2019
Born
Gregg Leonard Semenza

(1956-07-12) July 12, 1956 (age 68)
New York City, U.S.
EducationHarvard University (AB)
University of Pennsylvania (MD, PhD)
Known forHypoxia-inducible factors
SpouseLaura Kasch-Semenza
AwardsAlbert Lasker Award for Basic Medical Research (2016)
Nobel Prize in Physiology or Medicine (2019)
Scientific career
InstitutionsJohns Hopkins School of Medicine
ThesisMolecular genetic analysis of the silent carrier of beta thalassemia (haplotype) (1984)
Doctoral advisorsElias Schwartz
Saul Surrey

Gregg Leonard Semenza (born July 12, 1956) is an American pediatrician and Professor of Genetic Medicine at the Johns Hopkins School of Medicine. He serves as the director of the vascular program at the Institute for Cell Engineering.[1] He is a 2016 recipient of the Albert Lasker Award for Basic Medical Research.[2] He is known for his discovery of HIF-1, which allows cancer cells to adapt to oxygen-poor environments. He shared the 2019 Nobel Prize in Physiology or Medicine for "discoveries of how cells sense and adapt to oxygen availability" with William Kaelin Jr. and Peter J. Ratcliffe.[3][4] Semenza has had thirteen research papers retracted due to falsified data.[5]

  1. ^ "Gregg L. Semenza, M.D., Ph.D."
  2. ^ Foundation, Lasker. "Oxygen sensing – an essential process for survival – The Lasker Foundation". The Lasker Foundation.
  3. ^ "The Nobel Prize in Physiology or Medicine 2019". NobelPrize.org. Retrieved October 7, 2019.
  4. ^ Kolata, Gina; Specia, Megan (October 7, 2019). "Nobel Prize in Medicine Awarded for Research on How Cells Manage Oxygen – The prize was awarded to William G. Kaelin Jr., Peter J. Ratcliffe and Gregg L. Semenza for discoveries about how cells sense and adapt to oxygen availability". The New York Times. Retrieved October 8, 2019.
  5. ^ "Nobel prize-winner tallies two more retractions, bringing total to 13". Retraction Watch. September 13, 2024. Retrieved September 22, 2024.