| Group C nerve fiber | |
|---|---|
 C fiber not labeled, but substantia gelatinosa of Rolando is Rexed lamina II, labeled at upper left. | |
| Details | |
| Location | Central nervous system and peripheral nervous system |
| Function | nerve fiber |
| Anatomical terms of neuroanatomy | |
Group C nerve fibers are one of three classes of nerve fiber in the central nervous system (CNS) and peripheral nervous system (PNS). The C group fibers are unmyelinated and have a small diameter and low conduction velocity, whereas Groups A and B are myelinated. Group C fibers include postganglionic fibers in the autonomic nervous system (ANS), and nerve fibers at the dorsal roots (IV fiber). These fibers carry sensory information.
Damage or injury to nerve fibers causes neuropathic pain. Capsaicin activates C fibre vanilloid receptors, giving chili peppers a hot sensation.