| Gruffudd ap Llywelyn ap Iorwerth | |
|---|---|
 | |
| Born | c. 1196 |
| Died | 1 March 1244 Tower of London, England |
| Spouse | Senana ferch Caradog |
| Issue | Llywelyn ap Gruffudd Owain Goch ap Gruffydd Dafydd ap Gruffydd Rhodri ap Gruffudd |
| House | Aberffraw |
| Father | Llywelyn the Great |
| Mother | Tangwystl |
Gruffudd ap Llywelyn ap Iorwerth (c. 1196 – 1 March 1244) was a Welsh prince who was the first-born son of Llywelyn the Great ("Llywelyn Fawr"). His mother Tangwystl (c. 1180/1185 – c. 1210) probably died in childbirth.