Guanacastepene A

Guanacastepene A
Names
Preferred IUPAC name
(1R,2R,6S,8aR,10aR)-5-Formyl-6-hydroxy-8a,10a-dimethyl-3-oxo-1-(propan-2-yl)-1,2,3,6,7,8,8a,9,10,10a-decahydrobenzo[f]azulen-2-yl acetate
Identifiers
3D model (JSmol)
ChemSpider
UNII
  • InChI=1S/C22H30O5/c1-12(2)18-20(27-13(3)24)19(26)16-10-15-14(11-23)17(25)6-7-21(15,4)8-9-22(16,18)5/h10-12,17-18,20,25H,6-9H2,1-5H3/t17-,18-,20+,21-,22-/m0/s1 checkY
    Key: KCPNSIPCHJTGHJ-MYHSIESUSA-N checkY
  • InChI=1/C22H30O5/c1-12(2)18-20(27-13(3)24)19(26)16-10-15-14(11-23)17(25)6-7-21(15,4)8-9-22(16,18)5/h10-12,17-18,20,25H,6-9H2,1-5H3/t17-,18-,20+,21-,22-/m0/s1
    Key: KCPNSIPCHJTGHJ-MYHSIESUBP
  • O=C\C3=C2/C=C1/C(=O)[C@H](OC(=O)C)[C@@H]([C@]1(CC[C@@]2(CC[C@@H]3O)C)C)C(C)C
Properties
C22H30O5
Molar mass 374.477 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Guanacastepene A is a compound showing antibiotic activity. It is a diterpene that was extracted with hexane from a Costa Rican fungus, CR115, found on the branches of the Daphnopsis americana tree and purified by chromatography.[1]

  1. ^ Brady, Sean F.; Singh, Maya P.; Janso, Jeff E.; Clardy, Jon (2000). "Guanacastepene, a Fungal-Derived Diterpene Antibiotic with a New Carbon Skeleton". Journal of the American Chemical Society. 122 (9): 2116–2117. doi:10.1021/ja993835m.